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Enhancers looping to target genes

High-resolution maps of enhancer–promoter interactions in rare primary human T cell subsets and coronary artery smooth muscle cells link variants associated with autoimmune and cardiovascular diseases to target genes. This represents an important step forward for mapping genes involved in complex diseases.

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Correspondence to Gosia Trynka.

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Trynka, G. Enhancers looping to target genes. Nat Genet 49, 1564–1565 (2017).

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