The functional role of repetitive elements in mammalian genomes is still largely unexplored. A new study provides evidence that LINE-1 retrotransposons regulate chromatin dynamics and are essential for normal embryonic development in mice.
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Grow, E. A fine LINE-1 in mouse embryonic chromatin regulation. Nat Genet 49, 1418–1419 (2017). https://doi.org/10.1038/ng.3960