Three studies highlight DUX proteins as key transcription factors regulating embryonic genome activation in early mammalian development.
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References
Liang, H.L. et al. Nature 456, 400–403 (2008).
Hendrickson, P.G. et al. Nat. Genet. 49, 925–934 (2017).
De Iaco, A. et al. Nat. Genet. 49, 941–945 (2017).
Whiddon, J.L., Langford, A.T., Wong, C.-J., Zhong, J.W. & Tapscott, S.J. Nat. Genet. 49, 935–940 (2017).
Geng, L.N. et al. Dev. Cell 22, 38–51 (2012).
Young, J.M. et al. PLoS Genet. 9, e1003947 (2013).
Macfarlan, T.S. et al. Nature 487, 57–63 (2012).
Ishiuchi, T. et al. Nat. Struct. Mol. Biol. 22, 662–671 (2015).
Eckersley-Maslin, A.A. et al. Cell Rep. 17, 179–192 (2016).
Peaston, A.E. et al. Dev. Cell 7, 597–606 (2004).
Boškovic´, A. et al. Genes Dev. 28, 1042–1047 (2014).
Wu, J. et al. Nature 534, 652–657 (2016).
Choi, S.H. et al. Nucleic Acids Res. 44, 5161–5173 (2016).
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Iturbide, A., Torres-Padilla, ME. Starting embryonic transcription for the first time. Nat Genet 49, 820–821 (2017). https://doi.org/10.1038/ng.3880
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DOI: https://doi.org/10.1038/ng.3880