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Starting embryonic transcription for the first time

Three studies highlight DUX proteins as key transcription factors regulating embryonic genome activation in early mammalian development.

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Figure 1: Function of DUX proteins in mouse and human cells.

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Correspondence to Maria-Elena Torres-Padilla.

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Iturbide, A., Torres-Padilla, ME. Starting embryonic transcription for the first time. Nat Genet 49, 820–821 (2017). https://doi.org/10.1038/ng.3880

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