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Genetic interactions improve models of quantitative traits

A study of genetic variation in yeast has identified key quantitative trait loci (QTLs) that suppress the effects of variation at multiple other loci. These loci prove essential to accurately modeling yeast growth in response to different environments.

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Figure 1: Growth of yeast colonies based on genotypes at the suppressor hub QTL (rows) and its radial target QTLs (columns).

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Correspondence to Gregory W Carter.

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Tyler, A., Carter, G. Genetic interactions improve models of quantitative traits. Nat Genet 49, 486–488 (2017). https://doi.org/10.1038/ng.3829

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