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Genetic interactions improve models of quantitative traits

Nature Genetics volume 49, pages 486–488 (2017)Cite this article

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A study of genetic variation in yeast has identified key quantitative trait loci (QTLs) that suppress the effects of variation at multiple other loci. These loci prove essential to accurately modeling yeast growth in response to different environments.

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Figure 1: Growth of yeast colonies based on genotypes at the suppressor hub QTL (rows) and its radial target QTLs (columns).

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Authors and Affiliations

  1. Anna L. Tyler and Gregory W. Carter are at the Jackson Laboratory, Bar Harbor, Maine, USA.,

    Anna L Tyler & Gregory W Carter

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  1. Anna L Tyler
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  2. Gregory W Carter
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Correspondence to Gregory W Carter.

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The authors declare no competing financial interests.

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Tyler, A., Carter, G. Genetic interactions improve models of quantitative traits. Nat Genet 49, 486–488 (2017). https://doi.org/10.1038/ng.3829

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