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SWI/SNF complex in cancer

Four studies in this issue report new mechanisms underlying the function of the chromatin remodeling SWI/SNF complex in controlling gene expression and suppressing tumor development, providing valuable insights into the treatment of cancers harboring mutations in genes encoding SWI/SNF complex subunits.

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Figure 1: New remodeling mechanisms underline the tumor-suppressive function of the SWI/SNF complex.


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Correspondence to Chao Lu or C David Allis.

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Lu, C., Allis, C. SWI/SNF complex in cancer. Nat Genet 49, 178–179 (2017).

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