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Is a super-enhancer greater than the sum of its parts?

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Figure 1: Generalized linear models applied to published knockout data for the α-globin and Wap super-enhancers.


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We thank the authors of refs. 1 and 2 for providing their raw data. We thank B. Cohen, C. Danko and J. Lis for comments on the manuscript and J. Kinney for useful discussions about biophysical models. This research was supported in part by US National Institutes of Health grants GM102192 and HG007070. The content is solely the responsibility of the authors and does not necessarily represent the official views of the US National Institutes of Health.

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Correspondence to Adam Siepel.

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Dukler, N., Gulko, B., Huang, YF. et al. Is a super-enhancer greater than the sum of its parts?. Nat Genet 49, 2–3 (2017).

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