Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

The history of the Y chromosome in man

Studies of the Y chromosome over the past few decades have opened a window into the history of our species, through the reconstruction and exploitation of a patrilineal (Y-genealogical) tree based on several hundred single-nucleotide variants (SNVs). A new study validates, refines and extends this tree by incorporating >65,000 Y-linked variants identified in 1,244 men representing worldwide diversity.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

Figure 1: Clonal expansion of mutants in yeast and man.

Anne E. Dodson and Jasper Rine, 2015

References

  1. Poznik, G.D. et al. Nat. Genet. 48, 593–599 (2016).

    Article  CAS  Google Scholar 

  2. Underhill, P.A. et al. Nat. Genet. 26, 358–361 (2000).

    Article  CAS  Google Scholar 

  3. Y Chromosome Consortium. Genome Res. 12, 339–348 (2002).

  4. Karafet, T.M. et al. Genome Res. 18, 830–838 (2008).

    Article  CAS  Google Scholar 

  5. 1000 Genomes Project Consortium. Nature 526, 68–74 (2015).

  6. Jobling, M. & Tyler-Smith, C. Nat. Rev. Genet. 4, 598–612 (2003).

    Article  CAS  Google Scholar 

  7. Hallast, P. et al. Mol. Biol. Evol. 32, 661–673 (2015).

    Article  CAS  Google Scholar 

  8. Poznik, G.D. et al. Science 341, 562–565 (2013).

    Article  CAS  Google Scholar 

  9. Wei, W. et al. Genome Res. 23, 388–395 (2013).

    Article  CAS  Google Scholar 

  10. Zerjal, T. et al. Am. J. Hum. Genet. 72, 717–721 (2003).

    Article  CAS  Google Scholar 

  11. Balaresque, P. et al. Eur. J. Hum. Genet. 23, 1413–1422 (2015).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jennifer F Hughes.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Hughes, J., Page, D. The history of the Y chromosome in man. Nat Genet 48, 588–589 (2016). https://doi.org/10.1038/ng.3580

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ng.3580

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing