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The history of the Y chromosome in man

Nature Genetics volume 48, pages 588–589 (2016)Cite this article

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Studies of the Y chromosome over the past few decades have opened a window into the history of our species, through the reconstruction and exploitation of a patrilineal (Y-genealogical) tree based on several hundred single-nucleotide variants (SNVs). A new study validates, refines and extends this tree by incorporating >65,000 Y-linked variants identified in 1,244 men representing worldwide diversity.

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Figure 1: Clonal expansion of mutants in yeast and man.

Anne E. Dodson and Jasper Rine, 2015

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Authors and Affiliations

  1. Jennifer F. Hughes is at the Whitehead Institute, Cambridge, Massachusetts, USA,

    Jennifer F Hughes

  2. and Department of Biology, David C. Page is at the Whitehead Institute, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.,

    David C Page

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  1. Jennifer F Hughes
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  2. David C Page
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Correspondence to Jennifer F Hughes.

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The authors declare no competing financial interests.

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Hughes, J., Page, D. The history of the Y chromosome in man. Nat Genet 48, 588–589 (2016). https://doi.org/10.1038/ng.3580

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