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Legionella effectors reflect strength in diversity

Nature Genetics volume 48, pages 115–116 (2016)Cite this article

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The Legionella genus includes opportunistic human pathogenic species that invade human cells using effector proteins that evolved during association with their natural amoeba hosts. A new study compares the genomes of 41 Legionella species to identify nearly 6,000 effectors, providing insight into these species' evolution and pathogenic lifestyles.

Effector biology

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Figure 1: Legionella life cycle.

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Authors and Affiliations

  1. Iñaki Comas is in the Genomics and Health Unit, FISABIO Public Health, Valencia, Spain, and Centro de Investigación Biomédica en Red (CIBER) Epidemiología y Salud Pública, Instituto de Salud Carlos III, Madrid, Spain.,

    Iñaki Comas

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  1. Iñaki Comas
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Correspondence to Iñaki Comas.

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The author declares no competing financial interests.

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Comas, I. Legionella effectors reflect strength in diversity. Nat Genet 48, 115–116 (2016). https://doi.org/10.1038/ng.3492

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