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Building a staircase to precision medicine for biliary tract cancer

A new study has conducted a comprehensive exome and transcriptome analysis of a large number of intrahepatic, perihilar and distal cholangiocarcinomas and gallbladder cancers in Japanese patients. This study identifies many new alterations, confirms genetic differences in these distinct subtypes of biliary tract cancer and demonstrates that approximately 40% of described genetic aberrations are potentially targetable.

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Correspondence to Gregory J Gores.

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Razumilava, N., Gores, G. Building a staircase to precision medicine for biliary tract cancer. Nat Genet 47, 967–968 (2015). https://doi.org/10.1038/ng.3386

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