High-throughput analysis of the phenotypes of mouse genetic knockouts presents several challenges, such as systematic measurement biases that can vary with time. A report from the EUMODIC consortium presents data from 320 genetic knockouts generated using standardized phenotyping pipelines and new statistical analyses aimed at increasing reproducibility across centers.
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Mott, R. Genetic differential calculus. Nat Genet 47, 965–966 (2015). https://doi.org/10.1038/ng.3384
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DOI: https://doi.org/10.1038/ng.3384
