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A developmental program for Candida commensalism

Nature Genetics volume 45, pages 967968 (2013) | Download Citation

Candida albicans is a frequent pathogen of immunologically compromised individuals, but it is an even more common commensal of healthy humans, where it resides in the gut in a benign state. A new study shows that a specific commensal form of the fungus is induced in the gut through a developmental program that downregulates virulence factors and induces metabolic functions, enabling it to thrive on the nutrients that are available in the large intestine without damaging its host.

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Author information


  1. Neil A.R. Gow is in the Aberdeen Fungal Group, Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK.

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The author declares no competing financial interests.

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Correspondence to Neil A R Gow.

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