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A clear picture of renal cell carcinoma

Two recent studies describe the largest molecular profiling analyses to date of clear-cell renal cell carcinoma (ccRCC) and report remarkably similar findings. The recurrent pathway alterations identified in these studies open new avenues for therapeutic advances in this chemotherapy- and radiation-resistant disease.

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Figure 1: Integrated analyses of hundreds of ccRCC tumor samples identify recurrent pathway alterations.


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Correspondence to James J Hsieh.

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Hakimi, A., Pham, C. & Hsieh, J. A clear picture of renal cell carcinoma. Nat Genet 45, 849–850 (2013).

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