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Leveraging the species barrier to advance cancer therapy

The discovery of new therapeutic targets and the personalization of treatments are two active areas of cancer research. New studies suggest that a 'co-clinical' approach may expedite both therapeutic target validation and risk stratification in patients with advanced prostate cancer.

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Figure 1: Schematic of the cross-species approach for identifying and evaluating therapeutic targets.

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Correspondence to Peter S Nelson.

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Zhao, S., Nelson, P. Leveraging the species barrier to advance cancer therapy. Nat Genet 45, 718–720 (2013). https://doi.org/10.1038/ng.2683

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