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Digenic inheritance and Mendelian disease

Nature Genetics volume 44, pages 1291–1292 (2012)Cite this article

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Powerful genomic technologies, such as exome sequencing, are providing new insights into the genetics underlying Mendelian traits. A new study identifies a role for digenic inheritance and an epigenetic modifier in facioscapulohumeral muscular dystrophy type 2.

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Figure 1: Digenic inheritance and genetic interaction in FSHD2.

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  1. James R. Lupski is in the Department of Molecular and Human Genetics and the Department of Pediatrics at the Baylor College of Medicine, Houston, Texas, USA, and at the Texas Children's Hospital, Houston, Texas, USA.,

    James R Lupski

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  1. James R Lupski
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Correspondence to James R Lupski.

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Lupski, J. Digenic inheritance and Mendelian disease. Nat Genet 44, 1291–1292 (2012). https://doi.org/10.1038/ng.2479

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