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Acknowledgements

The authors are grateful to S. Pollack for assistance with EIGENSOFT. This work was made possible, in part, by the US National Institutes of Health (NIH; grant 5R01 MH084676) and, in part, by the International HIV Controllers Study, supported by the Collaboration for AIDS Vaccine Discovery of the Bill and Melinda Gates Foundation (to P.I.W.d.B.), and the AIDS Clinical Trials Group, supported by the NIH (grants AI069513, AI34835, AI069432, AI069423, AI069477, AI069501, AI069474, AI069428, AI69467, AI069415, Al32782, AI27661, AI25859, AI28568, AI30914, AI069495, AI069471, AI069532, AI069452, AI069450, AI069556, AI069484, AI069472, AI34853, AI069465, AI069511, AI38844, AI069424, AI069434, AI46370, AI68634, AI069502, AI069419, AI068636, RR024975 and AI077505). Sequencing of the SCZ control individuals was funded by the NIH (grant RC2MH089905), the Herman Foundation and the Stanley Medical Research Institute. N.O.S. was supported, in part, by an NIH Training Grant (T32-HL07604-25; Division of Cardiovascular Medicine, Brigham and Women's Hospital). B.M.N. was supported by a National Institute of Mental Health (NIMH) grant (1R01MH089208-01). R.D. is supported by a Canadian Institutes of Health Research Banting Postdoctoral Fellowship. The views expressed in this paper do not necessarily represent the views of the NIMH, NIH, Department of Health and Human Services (HHS) or the US government.

Author information

Author notes

    • Adam Kiezun
    • , Kiran Garimella
    • , Ron Do
    •  & Nathan O Stitziel

    These authors contributed equally to this work.

    • Alkes L Price
    • , Paul I W de Bakker
    • , Shaun M Purcell
    •  & Shamil R Sunyaev

    These authors jointly directed this work.

Affiliations

  1. Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

    • Adam Kiezun
    • , Paul J McLaren
    • , Paul I W de Bakker
    •  & Shamil R Sunyaev
  2. The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.

    • Adam Kiezun
    • , Kiran Garimella
    • , Ron Do
    • , Nathan O Stitziel
    • , Benjamin M Neale
    • , Paul J McLaren
    • , Namrata Gupta
    • , Jennifer L Moran
    • , Alkes L Price
    • , Paul I W de Bakker
    •  & Shamil R Sunyaev
  3. The Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.

    • Ron Do
    •  & Benjamin M Neale
  4. Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

    • Nathan O Stitziel
  5. Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.

    • Benjamin M Neale
    •  & Shaun M Purcell
  6. Department of Psychiatry, Friedman Brain Institute, Mount Sinai School of Medicine, New York, New York, USA.

    • Pamela Sklar
  7. Institute for Genomics and Multi-scale Biology, Mount Sinai School of Medicine, New York, New York, USA.

    • Pamela Sklar
  8. Department of Genetics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.

    • Patrick F Sullivan
  9. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

    • Christina M Hultman
    • , Paul Lichtenstein
    •  & Patrik Magnusson
  10. Division of Neuroscience and Basic Behavioral Science, National Institute of Mental Health, Bethesda, Maryland, USA.

    • Thomas Lehner
  11. Division of Intramural Research Program, National Institute of Mental Health, Bethesda, Maryland, USA.

    • Yin Yao Shugart
  12. Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.

    • Alkes L Price
  13. Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA.

    • Alkes L Price
  14. Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.

    • Paul I W de Bakker
  15. Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.

    • Paul I W de Bakker

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Correspondence to Shamil R Sunyaev.

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