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Self-fertilization sweeps up variation in the worm genome

A new study reports a comprehensive survey of genetic diversity in natural populations of the nematode Caenorhabditis elegans. Their analyses suggest that recent chromosome-scale selective sweeps have reduced C. elegans genetic diversity worldwide and strongly structured genetic variation across its genome.

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Figure 1: Influence of a self-fertilizing mating system on the patterns of genetic variation across the C. elegans genome.

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Correspondence to Patrick C Phillips.

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Phillips, P. Self-fertilization sweeps up variation in the worm genome. Nat Genet 44, 237–238 (2012). https://doi.org/10.1038/ng.2201

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