Table 1: Comparison of the Schistosoma haematobium genome with those of S. mansoni and S. japonicum

From: Whole-genome sequence of Schistosoma haematobium

Genomic featuresSchistosoma haematobiumSchistosoma mansoniSchistosoma japonicum
Estimate of genome size (Mb)385381403
Chromosome number (2n)8a88
Total number of base pairs within assembled contigs361,903,089374,944,597369,039,322
N50 contig (length (bp); total number >500 bp)21,744; n = 36,82616,320; n = 50,2926,121; n = 95,265
Total number of base pairs within assembled scaffolds385,110,549381,096,674402,705,545
N50 scaffold (length (bp); total number >1,000 bp in length)306,738; n = 7,475832,5415; n = 19,022176,869; n = 25,048
Proportion of genome that is coding (%)4.434.724.32
Number of putative coding genes13,07313,18413,469
Gene size (average bp ± s.d.; range)11,952 ± 16,273; 30–2013,397 ± 18,029; 84–240,19310,003 ± 12,980; 150–173,394
Average coding domain length (average bp ± s.d.; range)1,319 ± 1,502; 30–28,2121,344 ± 1,447; 60–22,9831,179 ± 1,201; 147–24,180
Average exon number per gene (average bp ± s.d.; range)5.4 ± 5.80; 1–1366.2 ± 6.24; 1–945.3 ± 4.70; 1–65
Gene exon length (average bp ± s.d.; range)246 ± 287; 1–9,737218 ± 236; 1–9,291223 ± 256; 6–6,326
Gene intron length (average bp ± s.d.; range)2,442 ± 2,958; 1–68,7542,331 ± 3,200; 1–67,2212,058 ± 2,679; 15–59,770
Total GC content (%)34.334.733.5
Repeat rate (%)47.24540.1
  1. aEstimate derived from a karyological study of S. haematobium16.