An efficient way to design genotyping arrays for fine mapping is to group phenotypes with common biology. The first application of the Immunochip to celiac disease provides an insightful view of what this strategy can achieve.
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Polychronakos, C. Fine points in mapping autoimmunity. Nat Genet 43, 1173–1174 (2011). https://doi.org/10.1038/ng.1015
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DOI: https://doi.org/10.1038/ng.1015