Drug's effects on embryonic blood-vessel growth may be the source of malformed limbs.
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References
Therapontos, C., Erskine, L., Gardner, E. R., Figg, W. D. & Vargesson, N. Proc. Natl Acad. Sci. USA doi:10.1073/pnas.0901505106 (2009).
Knobloch, J., Shaughnessy, J. D. Jr & Ruther, U. FASEB J. 21, 1410–1421 (2007).
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Ledford, H. How thalidomide makes its mark. Nature (2009). https://doi.org/10.1038/news.2009.462
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DOI: https://doi.org/10.1038/news.2009.462