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Release of Calcium induced by ‘Depolarisation’ of the Sarcoplasmic Reticulum Membrane

Nature New Biology volume 246, pages 216–218 (1973)Cite this article

Abstract

How depolarisation of the T system causes the release of calcium from the sarcoplasmic reticulum (SR) is the least understood process in excitation-contraction coupling in skeletal muscle. One of the possibilities suggested1 is that depolarisation of the T system may somehow cause a potential change across the SR membrane which, in turn, induces the release of calcium. If this is actually the case, it should be possible to release calcium by directly akering the membrane potential of the SR itself in the appropriate direction.

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Author notes

  1. MAKOTO ENDO

    Present address: Department of Pharmacology, Faculty of Medicine, University of Tokyo,

Authors and Affiliations

  1. Department of Biological Sciences, Purdue University, Lafayette, Indiana, 47907

    YASUKO NAKAJIMA & MAKOTO ENDO

Authors
  1. YASUKO NAKAJIMA
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  2. MAKOTO ENDO
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NAKAJIMA, Y., ENDO, M. Release of Calcium induced by ‘Depolarisation’ of the Sarcoplasmic Reticulum Membrane. Nature New Biology 246, 216–218 (1973). https://doi.org/10.1038/newbio246216a0

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