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Reaction of Human Smooth Muscle Antibody with Thymus Medullary Cells

Nature New Biology volume 246, pages 113–115 (1973)Cite this article

Abstract

SMOOTH muscle antibodies (SMA) are present in the sera of most cases of active chronic hepatitis (ACH)1, 2. They occur also in cases of acute hepatitis3, infectious mononucleosis4, 5 and cytomegalovirus (CMV) infection (G. B., unpublished). These antibodies are usually demonstrated by immunofluorescence using frozen sections of rat stomach or rat kidney. It has been shown that SMA react also with an actomyosin-like component present in the membranes of liver and other cells6. There is evidence that this antigen is different from the striated muscle myosin7.

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Author information

Authors and Affiliations

  1. Department of Immunology, Department of Tumour Biology, Karolinska Institutet School of Medicine, Stockholm

    ASTRID FAGRAEUS

  2. Department of Tumour Biology, Karolinska Institutet School of Medicine, Stockholm

    HAUW THE

  3. Department of Immmunology, National Bacteriological Laboratory, Stockholm

    GUNNEL BIBERFELD

Authors
  1. ASTRID FAGRAEUS
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  2. HAUW THE
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  3. GUNNEL BIBERFELD
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FAGRAEUS, A., THE, H. & BIBERFELD, G. Reaction of Human Smooth Muscle Antibody with Thymus Medullary Cells. Nature New Biology 246, 113–115 (1973). https://doi.org/10.1038/newbio246113a0

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