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Identification of a Critical Period during the S Phase for Activation of the Epstein-Barr Virus by 5-Iododeoxyuridine

Nature New Biology volume 244, pages 214–217 (1973)Cite this article

Abstract

HUMAN lymphoblastoid cells contain numerous, apparently complete, copies of the Epstein-Barr herpesvirus (EB virus) genome1,2. In some cell lines (producer cells), the viral genome may undergo spontaneous activation leading to viral antigen synthesis, while in other cell lines (non-producer cells) the viral genome rarely, if ever, activates spontaneously3.

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Authors and Affiliations

  1. Viral Carcinogenesis Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20014

    BERGE HAMPAR

  2. Flow Laboratories, Inc., Rockville, Maryland, 20852

    JEFFERY G. DERGE, LIDIA M. MARTOS, MALLE A. TAGAMETS, SUEH-YING CHANG & MRINAL CHAKRABARTY

Authors
  1. BERGE HAMPAR
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  2. JEFFERY G. DERGE
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  3. LIDIA M. MARTOS
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  4. MALLE A. TAGAMETS
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  5. SUEH-YING CHANG
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  6. MRINAL CHAKRABARTY
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HAMPAR, B., DERGE, J., MARTOS, L. et al. Identification of a Critical Period during the S Phase for Activation of the Epstein-Barr Virus by 5-Iododeoxyuridine. Nature New Biology 244, 214–217 (1973). https://doi.org/10.1038/newbio244214a0

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  • DOI: https://doi.org/10.1038/newbio244214a0

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