Abstract
DURING its life cycle, coliphage T4 expresses its genes in a controlled sequence. Early in infection, protein synthesis is primarily limited to products which are needed for T4 specific DNA metabolism1–4. After T4 DNA replication begins, most “early” proteins are no longer produced and instead the “late” proteins, which include phage structural and maturation elements and products necessary for lysis, are synthesized1–3,5–8.
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HORVITZ, H. Polypeptide Bound to the Host RNA Polymerase is Specified by T4 Control Gene 33. Nature New Biology 244, 137–140 (1973). https://doi.org/10.1038/newbio244137a0
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DOI: https://doi.org/10.1038/newbio244137a0