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Cytological Studies of Fat-storing Cells in the Liver of Rats given Large Doses of Vitamin A

Abstract

The “fat-storing” cell in the sinusoidal wall of the liver was first distinguished from Kiipffer and endothelial cells by Ito1–3, using light microscopy. The distinction was subsequently confirmed by electron microscopy4–15. Fat-storing cells have no phagocytic activity and occur in the perisinu-soidal space (Disse's space) where they are separated from the sinusoidal lumen by reticular fibres and by the endothelial lining incorporating Kiipffer cells4–15.

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KOBAYASHI, K., TAKAHASHI, Y. & SHIBASAKI, S. Cytological Studies of Fat-storing Cells in the Liver of Rats given Large Doses of Vitamin A. Nature New Biology 243, 186–188 (1973). https://doi.org/10.1038/newbio243186a0

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