Abstract
The “fat-storing” cell in the sinusoidal wall of the liver was first distinguished from Kiipffer and endothelial cells by Ito1–3, using light microscopy. The distinction was subsequently confirmed by electron microscopy4–15. Fat-storing cells have no phagocytic activity and occur in the perisinu-soidal space (Disse's space) where they are separated from the sinusoidal lumen by reticular fibres and by the endothelial lining incorporating Kiipffer cells4–15.
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References
Ito, T., Acta Anat. Nippon, 26, 42 (1951).
Ito, T., and Nemoto, M., Fol. Anat. Jap., 24, 243 (1952).
Ito, T., Satsuki, S., Kano, K., and Tsukagoshi, N., Arch. Histol. Jap., 3, 239 (1952).
Ito, T., Kitakanto, Igaku, 19, 429 (1969).
Yamagishi, M., Arch. Histol. Jap., 18, 223 (1959).
Novikoff, A. B., and Essner, E., Amer. J. Med., 29, 102 (1960).
Nakane, P. K., Anat. Rec., 145, 265 (1963).
Rouiller, Ch., and Jézéquel, A. M., The Liver, Morphology, Biochemistry, Physiology (edit. by Rouiller, Ch.), 1, 195 (Academic Press, London and NY, 1963).
Tanikawa, K., Yoshimura, K., and Gohara, Sh., Kurume Med. J., 13, 139 (1965).
Bronfenmajer, S., Schaffner, F., and Popper, H., Arch. Pathol., 82, 447 (1966).
Nicolescu, P., and Rouiller, Ch., Z. Zellforsch., 76, 313 (1967).
Tanikawa, K., and Tanaka, M., J. Electron Microscopy, 16, 205 (1967).
Ito, T., and Shibasaki, S., Arch. Histol. Jap., 29, 137 (1968).
Wisse, E., and Daems, W. Th., Mononuclear Phagocytes (edit. by Fürth, van R.), 200 (Blackwell, Oxford, 1970).
Kobayashi, K., and Takahashi, Y., Arch. Histol. Jap., 33, 421 (1971).
Popper, H., Arch. Pathol., 31, 766 (1941).
Popper, H., Physiol. Rev., 24, 205 (1944).
Popper, H., and Greenberg, R., Arch. Pathol., 32, 11 (1941).
Meyer, K. A., Popper, H., and Ragins, A. B., Arch. Surg., 43, 376 (1941).
Drummond, J. C., Gillding, H. P., and MacWalter, R. J., J. Physiol., 82, 75 (1934).
Rodahl, K., J. Nutr., 41, 399 (1950).
Nieman, C., and Klein Obbink, H. J., Vitamins and Hormones, 12, 69 (Academic Press, 1954).
Lane, B. P., Amer. J. Pathol., 53, 591 (1968).
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KOBAYASHI, K., TAKAHASHI, Y. & SHIBASAKI, S. Cytological Studies of Fat-storing Cells in the Liver of Rats given Large Doses of Vitamin A. Nature New Biology 243, 186–188 (1973). https://doi.org/10.1038/newbio243186a0
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DOI: https://doi.org/10.1038/newbio243186a0
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