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Giemsa Banding in Prematurely Condensed Chromosomes obtained by Cell Fusion

Nature New Biology volume 242, pages 106–107 (1973)Cite this article

Abstract

WHEN two mammalian cells fuse and one of the partners is in mitosis while the other is in interphase, the former will induce premature chromosome condensation (PCC) of the latter1. The prematurely condensed chromosomes are considerably longer and thinner than the regular metaphase chromosomes, and their morphology reflects the stage of the cell cycle of this interphase nucleus; single chromatid for G1, double chromatids for G2 and unevenly condensed chromatin for S.

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References

  1. Johnson, R. T., and Rao, P. N., Nature, 226, 717 (1970).

    Article  CAS  Google Scholar 

  2. Sumner, A. T., Evans, H. J., and Buckland, R., Nature New Biology, 232, 31 (1971).

    Article  CAS  Google Scholar 

  3. Drets, M. E., and Shaw, M. W., Proc. US Nat. Acad. Sci., 68, 2073 (1971).

    Article  CAS  Google Scholar 

  4. Seabright, M., Lancet, ii, 971 (1971).

    Article  Google Scholar 

  5. Patil, S., Rao, P. N., and Lubs, H., Mammal. Chromosomes Newslett., 13, 91 (1972).

    Google Scholar 

  6. Stefos, K., and Arrighi, F. E., Exp. Cell Res., 68, 228 (1971).

    Article  CAS  Google Scholar 

  7. Johnson, R. T., Rao, P. N., and Hughes, S. D., J. Cell. Physiol., 76, 151 (1970).

    Article  CAS  Google Scholar 

  8. Goldstein, S., and Lin, C. C., Exp. Cell Res., 70, 436 (1972).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Biology, University of Texas at Houston, M. D. Anderson Hospital and Tumor Institute, Houston, Texas

    W. UNAKUL

  2. Department of Zoology, Cambridge University, Cambridge

    R. T. JOHNSON

  3. Department of Developmental Therapeutics, University of Texas at Houston, M. D. Anderson Hospital and Tumor Institute, Houston, Texas

    P. N. RAO

  4. Department of Biology, University of Texas at Houston, M. D. Anderson Hospital and Tumor Institute, Houston, Texas

    T. C. HSU

Authors
  1. W. UNAKUL
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  2. R. T. JOHNSON
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  3. P. N. RAO
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  4. T. C. HSU
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UNAKUL, W., JOHNSON, R., RAO, P. et al. Giemsa Banding in Prematurely Condensed Chromosomes obtained by Cell Fusion. Nature New Biology 242, 106–107 (1973). https://doi.org/10.1038/newbio242106a0

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  • DOI: https://doi.org/10.1038/newbio242106a0

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