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Restricted Variation in the Glycolytic Enzymes of Human Brain and Erythrocytes

Nature New Biology volume 241, pages 229–233 (1973)Cite this article

Abstract

Glycolytic enzymes in man are limited in variation in the brain and erythrocytes. This variation may be accounted for by negative selection, eliminating mutations unfavourable to metabolic function.

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Author notes

  1. P. T. WADE COHEN

    Present address: Department of Biochemistry, Medical Sciences Institute, University of Dundee, Dundee, DD1 4HN

  2. S. -H. CHEN: Departments of Pediatrics, University of Washinton.

Authors and Affiliations

  1. Departments of Medicine and Genetics, Division of Medical Genetics, University of Washington School of Medicine, Seattle, Washington, 98195

    P. T. WADE COHEN, G. S. OMENN, A. G. MOTULSKY, S. -H. CHEN & E. R. GIBLETT

  2. King County Central Blood Bank, Seattle, Washington, 98104

    P. T. WADE COHEN, G. S. OMENN, A. G. MOTULSKY, S. -H. CHEN & E. R. GIBLETT

Authors
  1. P. T. WADE COHEN
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  2. G. S. OMENN
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  3. A. G. MOTULSKY
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  4. S. -H. CHEN
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  5. E. R. GIBLETT
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WADE COHEN, P., OMENN, G., MOTULSKY, A. et al. Restricted Variation in the Glycolytic Enzymes of Human Brain and Erythrocytes. Nature New Biology 241, 229–233 (1973). https://doi.org/10.1038/newbio241229a0

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  • DOI: https://doi.org/10.1038/newbio241229a0

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