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Evidence that the Cohesive Ends of Mature λ DNA are Generated by the Gene A Product

Nature New Biology volume 241, pages 16–17 (1973)Cite this article

Abstract

THE generation of the cohesive ends of λ DNA is generally believed to involve an enzyme or a group of enzymes which introduce two staggered single-chain scissions twelve bases apart (recent review in ref. 1). This hypothetical function has also been observed in the excision of a λ chromosome from a doubly lysogenic bacterium lacking all the known recombination functions, rec, red, and int2,3. This kind of excision cuts the prophage specifically between genes R and A, and is called Ter2.

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Authors and Affiliations

  1. Department of Chemistry, University of California, Berkeley, California, 94720

    JAMES C. WANG

  2. Department of Biochemistry, Stanford University, School of Medicine, Stanford, California, 94305

    A. D. KAISER

Authors
  1. JAMES C. WANG
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  2. A. D. KAISER
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WANG, J., KAISER, A. Evidence that the Cohesive Ends of Mature λ DNA are Generated by the Gene A Product. Nature New Biology 241, 16–17 (1973). https://doi.org/10.1038/newbio241016a0

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  • DOI: https://doi.org/10.1038/newbio241016a0

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