Abstract
AT least three forms of DNA-dependent RNA polymerase have been observed in eukaryotic organisms1–5. The multiple forms of the enzyme have been designated as types I, II and III, based on elution of RNA polymerase activity from ‘DEAE-Sephadex’1. It has been shown that type I is localized in the nucleolus and type II in the nucleoplasm of the cell2,6. The specific site of RNA polymerase III is not clear7,8, although some evidence indicates it may be of mitochondrial origin9. The role of multiple forms of RNA polymerase in developing systems is of particular interest and is under investigation in several laboratories10.
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WASSARMAN, P., HOLLINGER, T. & SMITH, L. RNA Polymerases in the Germinal Vesicle Contents of Ranapipiens Oocytes. Nature New Biology 240, 208–210 (1972). https://doi.org/10.1038/newbio240208a0
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DOI: https://doi.org/10.1038/newbio240208a0
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