Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letters to Editor
  • Published:

RNA Polymerases in the Germinal Vesicle Contents of Ranapipiens Oocytes

Abstract

AT least three forms of DNA-dependent RNA polymerase have been observed in eukaryotic organisms1–5. The multiple forms of the enzyme have been designated as types I, II and III, based on elution of RNA polymerase activity from ‘DEAE-Sephadex’1. It has been shown that type I is localized in the nucleolus and type II in the nucleoplasm of the cell2,6. The specific site of RNA polymerase III is not clear7,8, although some evidence indicates it may be of mitochondrial origin9. The role of multiple forms of RNA polymerase in developing systems is of particular interest and is under investigation in several laboratories10.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Roeder, R. G., and Rutter, W. J., Nature, 224, 234 (1969).

    Article  CAS  Google Scholar 

  2. Roeder, R. G., and Rutter, W. J., Proc. US Nat. Acad. Sci., 65, 675 (1970).

    Article  CAS  Google Scholar 

  3. Roeder, R. G., and Rutter, W. J., Biochemistry, 9, 2543 (1970).

    Article  CAS  Google Scholar 

  4. Roeder, R. G., Reeder, R. H., and Brown, D. D., Cold Spring Harbor Symp. Quant. Biol., 35, 727 (1970).

    Article  CAS  Google Scholar 

  5. Blatti, S. P., Ingles, C. J., Lindell, T. J., Morris, P. W., Weaver, R. F., Weinberg, F., and Rutter, W. J., Cold Spring Harbor Symp. Quant. Biol., 35, 649 (1970).

    Article  CAS  Google Scholar 

  6. Jacob, S. T., Sajdel, E., and Munro, H. N., Biochem. Biophys. Res. Commun., 38, 765 (1970).

    Article  CAS  Google Scholar 

  7. Eccleshall, R., and Criddle, R. S., Fed. Proc., 31, 472 (1972).

    Google Scholar 

  8. Benson, R. W., Fed. Proc., 31, 472 (1972).

    Google Scholar 

  9. Horgen, P. A., and Griffin, D. H., Nature, 234, 17 (1971).

    Article  CAS  Google Scholar 

  10. Cold Spring Harbor Symp. Quant. Biol., 35 (1970).

  11. Strain, G. C., Mullinix, K. P., and Bogorad, L., Proc. US Nat. Acad. Sci., 68, 2647 (1971).

    Article  CAS  Google Scholar 

  12. Weaver, R. F., Blatti, S., and Rutter, W. J., Proc US Nat. Acad. Sci., 68, 2994 (1971).

    Article  CAS  Google Scholar 

  13. Brown, D. D., and Dawid, I. B., Science, 160, 272 (1968).

    Article  CAS  Google Scholar 

  14. Crippa, M., Nature, 227, 1138 (1970).

    Article  CAS  Google Scholar 

  15. Crippa, M., Tocchini-Valentini, G. P., and Andronica, F., Oogenesis (edit. by Biggers, J. D., and Schuetz, A. W.) (University Park, Baltimore, in the press).

  16. Tocchini-Valentini, G. P., and Crippa, M., Cold Spring Harbor Symp. Quant. Biol., 35, 737 (1970).

    Article  CAS  Google Scholar 

  17. Lindell, T. J., Weinberg, F., Morris, P. W., Roeder, R. G., and Rutter, W. J., Science, 170, 447 (1970).

    Article  CAS  Google Scholar 

  18. Brown, D. D., and Littna, E., J. Mol. Biol., 20, 81 (1966).

    Article  CAS  Google Scholar 

  19. Watson, J. D., Molecular Biology of the Gene (Benjamin, New York, 1970).

    Google Scholar 

  20. Smith, L. D., and Ecker, R. E., Curr. Top. Dev. Biol., 5, 1 (1970).

    Article  Google Scholar 

  21. Briggs, R. W., and Cassens, G., Proc. US Nat. Acad. Sci., 55, 1103 (1966).

    Article  CAS  Google Scholar 

  22. Gurdon, J. B., and Speight, V. A., Exp. Cell Res., 55, 253 (1969).

    Article  CAS  Google Scholar 

  23. Gurdon, J. B., and Woodland, H. R., Curr. Top. Dev. Biol., 5, 39 (1970).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

WASSARMAN, P., HOLLINGER, T. & SMITH, L. RNA Polymerases in the Germinal Vesicle Contents of Ranapipiens Oocytes. Nature New Biology 240, 208–210 (1972). https://doi.org/10.1038/newbio240208a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/newbio240208a0

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing