Abstract
MICROTUBULES appear to play an important role in maintaining neurites of mouse neuroblastoma cells1 and of cultured chick spinal ganglia2 under normal in vitro conditions, perhaps serving as cytoskeletal elements3. However, a feature of many kinds of microtubules is their dissociation upon exposure to cold3–6. Usually, exposure to a temperature of 0–4° C for 30–60 min is sufficient to depolymerize such microtubules and often results in an alteration of cellular form.
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References
Prasad, K. N., Cytobiologie, 5, 265 (1972).
Daniels, M. P., J. Cell Biol., 53, 164 (1972).
Tilney, L. G., and Porter, K. R., J. Cell Biol., 34, 327 (1967).
Roth, L. E., J. Cell Biol., 34, 47 (1967).
Behnke, O., and Forer, A., J. Cell Sci., 2, 169 (1967).
Rodriguez-Echandia, E. L., and Piezzi, R. S., J. Cell Biol., 39, 491 (1968).
Hsie, A. W., and Puck, T. T., Proc. US Nat. Acad. Sci., 68, 358 (1971).
Sheppard, J. R., Proc. US Nat. Acad. Sci., 68, 1316 (1971).
Johnson, G. S., Friedman, R. M., and Pastan, I., Proc. US Nat. Acad. Sci., 68, 425 (1971).
Prasad, K. N., and Hsie, A. W., Nature New Biology, 233, 141 (1971).
Furmanski, P., Silverman, D. J., and Lubin, M., Nature, 233, 413 (1971).
Roisen, F. J., Murphy, R. A., Pichichero, M. E., and Braden, W. G., Science, 175, 73 (1972).
Branson, S. H., Exp. Cell Res., 65, 253 (1970).
Rasmussen, H., Science, 170, 404 (1970).
Goldman, R. D., and Rebhun, L. I., J. Cell Sci., 4, 179 (1969).
Kuo, J. F., and Greengard, P., J. Biol. Chem., 244, 3417 (1969).
Goodman, D. B. P., Rasmussen, H., DiBella, F., and Guthrow, C. E., Proc. US Nat. Acad. Sci., 67, 652 (1970).
Greengard, P., and Kuo, J. F., in Role of Cyclic AMP in Cell Function (edit. by Greengard, P., and Costa, E.), 287 (Raven Press, New York, 1970).
Johnson, G. S., and Pastan, I., Nature New Biology, 236, 247 (1972).
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KIRKLAND, W., BURTON, P. Cyclic Adenosine Monophosphate-mediated Stabilization of Mouse Neuroblastoma Cell Neunte Microtubules exposed to Low Temperature. Nature New Biology 240, 205–207 (1972). https://doi.org/10.1038/newbio240205a0
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DOI: https://doi.org/10.1038/newbio240205a0
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