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Pseudopodia Formation by Secretory Granules

Abstract

IN the process of exocytosis the membranes of the secretory granule1,2 and the cell come together and an opening is formed at the point of coalescence. Thus the granule content is placed outside the cell while the other cell components remain inside. The granule or the cell membrane must undergo some activation which would bring the two structures into contact with each other prior to the actual fusion process. Such a reaction was sought for in the present study using preparations of rat salivary parotid gland in which massive enzyme secretion is readily induced by catecholamines via adenosine-3′,5′ monophosphate (cyclic AMP)3–6.

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SCHRAMM, M., SELINGER, Z., SALOMON, Y. et al. Pseudopodia Formation by Secretory Granules. Nature New Biology 240, 203–205 (1972). https://doi.org/10.1038/newbio240203a0

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