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Adenosine Inhibition of Human Platelet Aggregation by ADP

Nature New Biology volume 239, pages 211–213 (1972)Cite this article

Abstract

WE have shown that in human platelet-rich plasma, inosine is a concentration-dependent inhibitor of adenosine incorporation into platelets1,2, and at high concentrations inosine inhibits adenosine decomposition3. This prompted us to investigate the effect of inosine and other adenosine decomposition products on aggregation of human platelets in vivo by ADP.

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References

  1. Jenkins, C. S. P., Caen, J. P., Vainer, H., & Pokutecky, J., Nature New Biology, 239, 210 (1972).

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Authors and Affiliations

  1. Department of Hemostasis, Institut de Recherches sur les Maladies du Sang, Hôpital Saint-Louis, Paris, 10

    J. P. CAEN, C. S. P. JENKINS, H. MICHEL & R. BELLANGER

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  1. J. P. CAEN
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  2. C. S. P. JENKINS
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  3. H. MICHEL
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  4. R. BELLANGER
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CAEN, J., JENKINS, C., MICHEL, H. et al. Adenosine Inhibition of Human Platelet Aggregation by ADP. Nature New Biology 239, 211–213 (1972). https://doi.org/10.1038/newbio239211a0

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  • DOI: https://doi.org/10.1038/newbio239211a0

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