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Steroid Control of Genomic Expression in Embryonic Chick Retina

Nature New Biology volume 237, pages 121–125 (1972)Cite this article

Abstract

NEURAL retinas of the embryonic chick show consistent measurable responses in which the enzyme glutamine synthetase (GS) is induced when treated in vivo and in vitro with corticosteroids1–4. RNA transcription and protein synthesis are both required for induction of enzyme5–7 in agreement with evidence from other systems, which suggests that hormones affect protein biosynthesis in target tissues by differential gene activity8–10. None of these studies has demonstrated a selective increase, however, in the concentration of a specific fraction of transcribed RNA after hormone addition.

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Authors and Affiliations

  1. Department of Biology, and Department of Histology and Embryology, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, 19104

    ROBERT J. SCHWARTZ

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  1. ROBERT J. SCHWARTZ
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SCHWARTZ, R. Steroid Control of Genomic Expression in Embryonic Chick Retina. Nature New Biology 237, 121–125 (1972). https://doi.org/10.1038/newbio237121a0

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