Covalently Linked RNA-DNA Molecule as Initial Product of RNA Tumour Virus DNA Polymerase

Abstract

Reverse transcriptase from avian myeloblastosis virus initially synthesizes from endogenous RNA template a covalently linked DNA–RNA species, which Verma et al. suggest contains a small RNA primer molecule.

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References

  1. 1

    Baltimore, D., Nature, 226, 1209 (1970).

  2. 2

    Temin, H., and Mizutani, S., Nature, 226, 1211 (1970).

  3. 3

    Spiegelman, S., Burny, A., Das, M. R., Keydar, J., Schlom, J., Travnicek, M., and Watson, K., Nature, 227, 563 (1970).

  4. 4

    Rokutanda, M., Rokutanda, H., Green, M., Fujinaga, K., Ray, R. K., and Gurgo, C., Nature, 227, 1026 (1970).

  5. 5

    Duesberg, P. H., and Canaani, E., Virology, 42, 783 (1970).

  6. 6

    Spiegelman, S., Burny, A., Das, M. R., Keydar, J., Schlom, J., Travnicek, M., and Watson, K., Nature, 227, 1029 (1970).

  7. 7

    Spiegelman, S., Burny, A., Das, M. R., Keydar, J., Schlom, J., Travnicek, M., and Watson, K., Nature, 228, 430 (1970).

  8. 8

    Mizutani, S., Boettiger, D., and Temin, H. M., Nature, 228, 424 (1970).

  9. 9

    Riman, J., and Beaudreau, G. S., Nature, 228, 427 (1970).

  10. 10

    Baltimore, D., and Smoler, D., Proc. US Nat. Acad. Sci., 68, 1507 (1971).

  11. 11

    Baltimore, D., and Smoler, D., Proc. Third Annual Miami Winter Biochemistry Symp. (in the press).

  12. 12

    Baltimore, D., Smoler, D., Manly, K. F., and Bromfeld, E., in Ciba Foundation Symp. The Strategy of the Viral Genome (Churchill, London, in the press).

  13. 13

    Manly, K., Smoler, D. F., Bromfeld, E., and Baltimore, D., J. Virol., 7, 106 (1971).

  14. 14

    Fujinaga, K., Parsons, J. T., Beard, J. W., Beard, D., and Green, M., Proc. US Nat. Acad. Sci., 67, 1432 (1970).

  15. 15

    Garapin, A.-C., McDonnell, J. P., Levinson, W. E., Quintrell, N. I. Fanshier, L., and Bishop, J. M., J. Virol., 6, 589 (1970).

  16. 16

    Chamberlain, M., and Berg, P., J. Mol. Biol., 8, 297 (1964).

  17. 17

    Erikson, E., and Erikson, R. L., J. Virol, (in the press).

  18. 18

    Jacob, F., and Brenner, S., CR Acad. Sci., 256, 298 (1963).

  19. 19

    Jacob, F., Brenner, S., and Cuzin, F., Cold Spring Harbor Symp. Quant. Biol., 28, 329 (1963).

  20. 20

    Linn, S., and Lehman, I. R., J. Biol. Chem., 240, 1287 and 1294 (1965).

  21. 21

    Rabin, Preiss, and Fraser, Preparative Biochemistry (in the press).

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