Abstract
THE two antigenic subclasses of human γA myeloma proteins that have been identified are γA1 and γA2 (refs. 1-3). H—H interchain disulphide bonds are present in molecules of both subclasses, but H—L interchain disulphide bonds are present only in γA1 proteins and the minor allotype of γA2, Am 2–(ref. 4). Light chains of Am 2+ γA proteins occur as disulphide bonded dimers non-covalently linked to the heavy chains5.
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ABEL, C., GREY, H. Structural Differences in the Hinge Region of Human Gamma A Myeloma Proteins of Different Subclasses. Nature New Biology 233, 29–31 (1971). https://doi.org/10.1038/newbio233029a0
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DOI: https://doi.org/10.1038/newbio233029a0
