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Ontogeny of Mouse Liver Peroxisomes and Catalase Isozymes

Nature New Biology volume 232, pages 218–220 (1971)Cite this article

Abstract

PEROXISOMES are cytoplasmic organelles which occur in liver and kidney cells of higher animals and in lower forms of life. They have a unique enzyme composition and function in the oxidation of specific substrates by oxidases1. Catalase (hydrogen peroxide: hydrogen peroxide oxidoreductase E.C. 1.11.1.6) is an essential component of this oxidizing system which facilitates the catalytic or peroxidatic destruction of hydrogen peroxide. Large granular catalase activity serves as a marker for the organelle and has been used here to describe the ontogeny of peroxisomes in mouse liver. The results indicate that bursts of peroxisomal synthesis occur during the development of the mouse liver, particularly in the early postnatal stages and during maturation.

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Authors and Affiliations

  1. School of Biological Sciences, La Trobe University, Bundoora, Victoria, 3083

    R. S. HOLMES

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  1. R. S. HOLMES
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HOLMES, R. Ontogeny of Mouse Liver Peroxisomes and Catalase Isozymes. Nature New Biology 232, 218–220 (1971). https://doi.org/10.1038/newbio232218a0

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