Abstract
Platelets in the blood of volunteers who have taken aspirin can no longer produce prostaglandins.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
We are sorry, but there is no personal subscription option available for your country.
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Morris, C. D. W., Lancet, i, 279 (1967).
Weiss, W. J., and Aledort, L. M., Lancet, ii, 495 (1967).
Zucker, M. B., and Peterson, J., Proc. Soc. Exp. Biol. Med., 127, 547 (1968).
O'Brien, J. R., Lancet, i, 779 (1968).
Macmillan, D. C., Lancet, i, 1151 (1968).
Packham, M. A., Nishizawa, E. E., and Mustard, J. F., Biochem. Pharmacol., Suppl., 171 (1968).
Crunkhorn, P., and Willis, A. L., Brit. J. Pharmacol., 36, 216P (1969).
Crunkhorn, P., and Willis, A. L., Brit. J. Pharmacol., 41, 49 (1971).
Piper, Priscilla J., and Vane, J. R., Nature, 223, 29 (1969).
Smith, J. B., and Willis, A. L., Brit. J. Pharmacol., 40, 545P (1970).
Vane, J. R., Nature New Biology, 231, 232 (1971).
Ferreira, G. H., Moncada, S., and Vane, J. R., Nature New Biology, 231, 237 (1971).
Holmsen, H., Day, H. J., and Stormorken, H., Scand. J. Haematol., Suppl., 8 (1969).
Smith, A. D., and Winkler, M., Biochem. J., 108, 867 (1968).
Bartels, J., Kunze, H., Vogt, W., and Wille, G., Naunyn-Schmiede-berg's Arch. Pharmak. Exp. Pathol., 266, 199 (1970).
Bergström, S., Danielsson, H., and Samuelsson, B., Biochim. Biophys. Acta, 90, 207 (1964).
Samuelsson, B., Progr. Biochem. Pharmacol., 3, 59 (1967).
Mills, D. C. B., Robb, I. A., and Roberts, G. C. K., J. Physiol., 195, 715 (1968).
Haslam, R. J., Nature, 202, 765 (1964).
Willis, A. L., J. Pharm. Pharmacol., 21, 126 (1969).
. Holmsen, H., and Day, H. J., J. Lab. Clin. Med., 75, 840 (1970).
Cooper, M. F., and Webster, G. R., J. Neurochem., 17, 1543 (1970).
Davey, M. G., and Lüscher, E. F., Biochim. Biophys. Acta, 165, 490 (1968).
Evans, G., Packham, M. A., Nishizawa, E. E., Mustard, J. F., and Murphy, E. A., J. Exp. Med., 128, 877 (1968).
Greaves, M. W., Sondergaard, J., and McDonald-Gibson, W., Brit. Med. J., 2, 258 (1971).
Juhlin, L., and Michaëlsson, G., Acta Dermatol. Vener., 49, 251 (1969).
Willis, A. L., in Prostaglandins, Peptides and Amines (edit. by Mantegazza, P., and Horton, E. W.), 31 (Academic Press, London, 1969).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
SMITH, J., WILLIS, A. Aspirin Selectively Inhibits Prostaglandin Production in Human Platelets. Nature New Biology 231, 235–237 (1971). https://doi.org/10.1038/newbio231235a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/newbio231235a0
This article is cited by
-
Aspirin protects against genotoxicity by promoting genome repair
Cell Research (2023)
-
Effects of ezetimibe and anticoagulant combined therapy on progressing stroke: a randomized, placebo-controlled study
Journal of Neurology (2016)
-
Prostanoids and NSAIDs in Cardiovascular Biology and Disease
Current Atherosclerosis Reports (2015)