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In vitro Detection of Enhancing Antibody by the Macrophage Migration Test

Abstract

THE immunological basis of enhanced allograft survival in inbred strains of mice is well established: humoral antibody, by some mechanism which is not yet clear, interferes with the cell-mediated host response to alloantigens1. Various in vitro correlates of transplantation immunity in the mouse have been developed2–9 and we have adapted one, the technique of macrophage migration from capillary tubes9, as an in vitro method to detect enhancing antibody.

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BERNSTEIN, I., WRIGHT, P. In vitro Detection of Enhancing Antibody by the Macrophage Migration Test. Nature New Biology 231, 25–26 (1971). https://doi.org/10.1038/newbio231025a0

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