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Evidence for Duplication of the Haemoglobin γ Chain Locus in Macaca nemestrina

Nature New Biology volume 229, pages 145–147 (1971)Cite this article

Abstract

FOETAL haemoglobins are synthesized by several, and perhaps all, of the Anthropoidea during intrauterine development; little is known of the primary structures of their γ chains, but they are presumed to bear close structural resemblances to human γ chains. Until recently, the synthesis of human γ chains was thought to be controlled by a single structural locus; Schroeder et al.1 showed that at least two, and possibly four, γ-chain loci are active in human foetuses. So far theirs has been the only report indicating that there are two or more γ-chain loci in any mammal. We have evidence for the existence of duplicate haemoglobin γ-chain loci in Macaca nemestrina (pig-tailed macaques).

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Authors and Affiliations

  1. Division of Medical Genetics, Department of Medicine and Regional Primate Research Center, University of Washington, Seattle, Washington, 98105

    PETER E. NUTE

  2. Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, Washington, 98105

    GEORGE STAMATOYANNOPOULOS

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  1. PETER E. NUTE
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  2. GEORGE STAMATOYANNOPOULOS
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NUTE, P., STAMATOYANNOPOULOS, G. Evidence for Duplication of the Haemoglobin γ Chain Locus in Macaca nemestrina. Nature New Biology 229, 145–147 (1971). https://doi.org/10.1038/newbio229145a0

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