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  • Case Study
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Low-grade phyllodes tumor of the seminal vesicle treated with laparoscopic excision

Nature Clinical Practice Urology volume 4, pages 395–400 (2007)Cite this article

Abstract

Background A 43-year-old man presented with a 2-year history of hematospermia and dull ache in the left testis. On physical examination he had left epididymal tenderness and a normal digital rectal examination.

Investigations Transrectal ultrasonography and MRI.

Diagnosis Low-grade phyllodes tumor of the left seminal vesicle.

Management Laparoscopic excision of the left seminal vesicle.

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Figure 1: MRI scan showing a 3 × 2 cm low-signal, soft tissue mass within the left seminal vesicle
Figure 2: Port configuration for laparoscopic excision of the left seminal vesicle
Figure 3: Distorted and bulbous seminal vesicle with an intact and smooth external surface
Figure 4: Hematoxylin and eosin-stained low-power photomicrograph of the tumor
Figure 5: Photomicrograph showing lining epithelium with focal apocrine snouting
Figure 6: Photomicrograph showing artefactual tubular invaginations into the stroma, lined by the same epithelium
Figure 7: Photomicrograph showing hypocellular, hyalinised stroma
Figure 8: Photomicrograph showing very infrequent mitotic figures within the stroma
Figure 9: High-power photomicrograph of lining epithelium, showing focal, mild stratification of cells and very occasional mitotic figures

References

  1. Tanaka T et al. (1987) Primary adenocarcinoma of the seminal vesicle. Hum Pathol 18: 200–202

    Article  CAS  Google Scholar 

  2. Dalgaard JB and Giertsen JC (1956) Primary carcinoma of the seminal vesicle. Acta Pathol Microbiol Scand 39: 255–267

    Article  CAS  Google Scholar 

  3. Bostwick DG (1996) Seminal Vesicles. In Urologic Surgical Pathology, 423 (Eds Bostwick DG and Eble JN) St Louis: Mosby Publishers

    Google Scholar 

  4. Slayter MV et al. (1994) Histogenesis of induced prostate and seminal vesicle carcinoma in Lobund–Wistar rats: a system for histological scoring and grading. Cancer Res 54: 1440–1445

    CAS  PubMed  Google Scholar 

  5. Ohori M et al. (1993) The mechanisms and prognostic significance of seminal vesicle involvement by prostate cancer. Am J Surg Pathol 17: 1252–1261

    Article  CAS  Google Scholar 

  6. Ro JY et al. (1987) Seminal vesicle involvement by in situ and invasive transitional cell carcinoma of the bladder. Am J Surg Pathol 11: 951–958

    Article  CAS  Google Scholar 

  7. Iczkowski KA et al. (2004) Tumours of the seminal vesicles. In World Health Organisation Classification of Tumours, volume 7: pathology and genetics of tumours of the urinary system and male genital organs, 214 (Eds John NE et al.) Lyon: IARC Press

    Google Scholar 

  8. Hawkins RE et al. (1992) The clinical and histologic criteria that predict metastases from cystosarcoma phyllodes. Cancer 69: 141–147

    Article  CAS  Google Scholar 

  9. Fain JS et al. (1993) Cystosarcoma phyllodes of the seminal vesicle. Cancer 71: 2055–2061

    Article  CAS  Google Scholar 

  10. Abe H et al. (2002) Cystosarcoma phyllodes of the seminal vesicle. Int J Urol 9: 599–601

    Article  Google Scholar 

  11. Son HJ et al. (2004) Phyllodes tumor of the seminal vesicle: case report and literature review. Pathol Int 54: 924–929

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. MS Khan is a Consultant Urological Surgeon, L-U Zaheer is a House Officer in Urology, K Ahmed is a Senior House Officer in Surgery, D Cahill is a Consultant Urological Surgeon, C Horsefield is a Consultant Uropathologist, G Rottenberg is a Consultant Uroradiologist and P Dasgupta is a Consultant Urological Surgeon, all at Guy's Hospital, London, UK.,

    Mohammad S Khan, Lail-Umah Zaheer, Kamran Ahmed, Declan Cahill, Catherine Horsfield, Giles Rottenberg & Prokar Dasgupta

Authors
  1. Mohammad S Khan
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  2. Lail-Umah Zaheer
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  3. Kamran Ahmed
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  4. Declan Cahill
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  5. Catherine Horsfield
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  6. Giles Rottenberg
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  7. Prokar Dasgupta
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Corresponding author

Correspondence to Mohammad S Khan.

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The authors declare no competing financial interests.

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Cite this article

Khan, M., Zaheer, LU., Ahmed, K. et al. Low-grade phyllodes tumor of the seminal vesicle treated with laparoscopic excision. Nat Rev Urol 4, 395–400 (2007). https://doi.org/10.1038/ncpuro0837

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  • DOI: https://doi.org/10.1038/ncpuro0837

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