Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Case Study
  • Published:

A case of incidental adrenocortical oncocytoma

Nature Clinical Practice Urology volume 3, pages 618–621 (2006)Cite this article

Abstract

Background A 39-year-old female presented with an incidentally discovered left adrenal mass. She denied any history of hypertension, headaches, palpitations, muscle weakness, bruising easily, or fatigue. Physical examination was unremarkable.

Investigations Physical examination, laboratory analyses, CT scan and MRI.

Diagnosis Oncocytic adrenocortical tumor, or adrenal oncocytoma.

Management Adrenalectomy, gross and histopathologic examination, and follow-up radiologic imaging.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Microscopy of the adrenal oncocytoma.

References

  1. Chang A and Harawi SJ (1992) Oncocytes, oncocytosis and oncocytic tumors. Pathol Annu 27: 263–304

    PubMed  Google Scholar 

  2. Lin BT et al. (1998) Oncocytic adrenocortical neoplasms: a report of seven cases and review of the literature. Am J Surg Pathol 22: 603–614

    Article  CAS  Google Scholar 

  3. Bisceglia M et al. (2004) Adrenocortical oncocytic tumors: report of 10 cases and review of the literature. Int J Surg Pathol 12: 231–243

    Article  Google Scholar 

  4. Xiao GQ et al. (2005) Functioning adrenocortical oncocytoma: a case report and review of the literature. Ann Diagn Pathol 9: 295–297

    Article  Google Scholar 

  5. Aiba M and Fujibayashi M (2005) Histopathological diagnosis and prognostic factors in adrenocortical carcinoma. Endocr Pathol 16: 13–22

    Article  Google Scholar 

  6. Corsi A et al. (2002) Incidentally detected giant oncocytoma arising in retroperitoneal heterotopic adrenal tissue. Arch Pathol Lab Med 129: 1118–1122

    Google Scholar 

  7. Nguyen GK et al. (1992) Heterotopic adrenocortical oncocytoma. A case report with light and electron microscopic studies. Cancer 70: 2681–2684

    Article  CAS  Google Scholar 

  8. Segal S et al. (2001) Adrenocortical oncocytoma in pregnancy. Obstet Gynecol 98: 916–918

    CAS  PubMed  Google Scholar 

  9. Erlandson RA and Reuter VE (1991) Oncocytic adrenal cortical adenoma. Ultrastruct Pathol 15: 539–547

    Article  CAS  Google Scholar 

  10. Bégin LR (1992) Adrenocortical oncocytoma: case report with immunocytochemical and ultrastructural study. Virchows Arch A Pathol Anat Histopathol 421: 533–537

    Article  Google Scholar 

  11. Hoang MP et al. (2002) Oncocytic adrenocortical carcinoma: a morphologic, immunohistochemical and ultrastructural study of four cases. Mod Pathol 15: 973–978

    Article  Google Scholar 

  12. El-Naggar AK et al. (1991) Oncocytic adrenal cortical carcinoma. Ultrastruc Pathol 15: 549–556

    Article  CAS  Google Scholar 

  13. Medeiros LJ and Weiss LM (1992) New developments in the pathologic diagnosis of adrenal cortical neoplasms. Am J Clin Pathol 97: 73–83

    Article  CAS  Google Scholar 

  14. Stojadinovic A et al. (2003) Adrenocortical adenoma and carcinoma: histopathological and molecular comparative analysis. Mod Pathol 16: 742–751

    Article  Google Scholar 

  15. Copeland PM (1983) The incidentally discovered adrenal mass. Ann Inten Med 98: 940–945

    Article  CAS  Google Scholar 

  16. Belldegrun A et al. (1986) The incidentally discovered adrenal mass: a therapeutic dilemma—BWH experience 1976–1983. Surg Gynecol Obstet 163: 203–208

    CAS  PubMed  Google Scholar 

  17. Barzon L and Boscaro M (2000) Diagnosis and management of adrenal incidentalomas. J Urol 163: 398–407

    Article  CAS  Google Scholar 

  18. Staren ED and Prinz RA (1995) Selection of patients with adrenal incidentalomas for operation. Surg Clin North Am 75: 499–509

    Article  CAS  Google Scholar 

  19. Cerfolio RJ et al. (1993) Accuracy of computed tomography in predicting adrenal tumor size. Surg Gynecol Obstet 176: 307–309

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. resident in urology at New York Presbyterian Hospital–Weill Cornell Medical Center, NY, USA

    Richard Lee

  2. research pathologist and VE Reuter is the Vice-Chairman of Oncologic Surgical Pathology at Memorial Sloan–Kettering Cancer Center, New York, NY, USA

    Hikmat A Al-Ahmadie & Victor E Reuter

  3. Fellow in Urologic Oncology at the Mayo Clinic in Rochester, MN, USA

    Stephen A Boorjian

  4. Clinical Assistant Professor of Urology at the Baylor College of Medicine, Houston, TX, USA

    Ricardo R Gonzalez

  5. medical student at University of Illinois, Chicago, IL, USA

    Christian Badillo

  6. the Chief of the Division of Robotic Surgery at North Shore University Hospital, Manhasset, NY, USA

    Felix Badillo

  7. New York Presbyterian Hospital,

    Joph Steckel

  8. New York Presbyterian–North Shore University Hospital residency rotation, NY, USA

    Joph Steckel

Authors
  1. Richard Lee
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Hikmat A Al-Ahmadie
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Stephen A Boorjian
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Ricardo R Gonzalez
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Christian Badillo
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Felix Badillo
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Victor E Reuter
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Joph Steckel
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Richard Lee.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lee, R., Al-Ahmadie, H., Boorjian, S. et al. A case of incidental adrenocortical oncocytoma. Nat Rev Urol 3, 618–621 (2006). https://doi.org/10.1038/ncpuro0631

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ncpuro0631

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing