Abstract
Background A 36-year-old black male with sickle-cell disease, asthma, and dyslipidemia presented with shortness of breath, chest pain, lethargy, and recent fever. Physical examination revealed mild respiratory distress.
Investigations Chest X-ray, CT, abdominal ultrasound, and MRI.
Diagnosis Renal medullary carcinoma.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Berman LB (1974) Sickle cell nephropathy. JAMA 228: 1279
Davis CJ Jr et al. (1995) Renal medullary carcinoma. The seventh sickle cell nephropathy. Am J Surg Pathol 19: 1–11
Coogan CL et al. (1998) Renal medullary carcinoma in patients with sickle cell trait. Urology 51: 1049–1050
Mostofi FK et al. (1957) Lesions in kidneys removed for unilateral hematuria in sickle-cell disease. AMA Arch Pathol 63: 336–351
Swartz MA et al. (2002) Renal medullary carcinoma: clinical, pathologic, immunohistochemical, and genetic analysis with pathogenetic implications. Urology 60: 1083–1089
Larsen DM et al. (1998) Renal medullary carcinoma: report of a case with positive urinary cytology. Diagn Cytopathol 18: 276–279
Pickhardt PJ (1996) Renal medullary carcinoma: an aggressive neoplasm in patients with sickle cell trait. Abdomin Imaging 23: 531–532
Yang XJ (2004) Gene expression profiling of renal medullary carcinoma: potential clinical relevance. Cancer 100: 976–985
Selby DM (2000) Renal medullary carcinoma: can early diagnosis lead to long term survival? Urology 163: 1238
Warren KE et al. (1999) Renal medullary carcinoma in an adolescent with sickle cell trait. Pediatrics 103: E22–25
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Sathyamoorthy, K., Teo, A. & Atallah, M. Renal medullary carcinoma in a patient with sickle-cell disease. Nat Rev Urol 3, 279–283 (2006). https://doi.org/10.1038/ncpuro0483
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1038/ncpuro0483
This article is cited by
-
Renal collecting duct carcinoma with extensive coagulative necrosis mimicking anemic infarct: report of a case and the literature review
Diagnostic Pathology (2013)
-
Uncommon and recently described renal carcinomas
Modern Pathology (2009)