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Childhood CNS vasculitis: a treatable cause of new neurological deficit in children

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  1. Calabrese LH and Mallek JA (1988) Primary angiitis of the central nervous system. Report of 8 new cases, review of the literature, and proposal for diagnostic criteria. Medicine (Baltimore) 67: 20–39

    Article  CAS  Google Scholar 

  2. Calabrese LH et al. (1992) Primary angiitis of the central nervous system: diagnostic criteria and clinical approach. Cleve Clin J Med 59: 293–306

    Article  CAS  Google Scholar 

  3. Lanthier S et al. (2001) Isolated angiitis of the CNS in children. Neurology 56: 837–842

    Article  CAS  Google Scholar 

  4. Gallagher KT et al. (2001) Primary angiitis of the central nervous system in children: 5 cases. J Rheumatol 28: 616–623

    CAS  PubMed  Google Scholar 

  5. Benseler SM et al. (2006) Primary central nervous system vasculitis in children. Arthritis Rheum 54: 1291–1297

    Article  Google Scholar 

  6. Elbers J and Benseler SM (2008) Central nervous system vasculitis in children. Curr Opin Rheumatol 20: 47–54

    Article  Google Scholar 

  7. Aviv RI et al. (2006) MR imaging and angiography of primary CNS vasculitis of childhood. AJNR Am J Neuroradiol 27: 192–199

    CAS  PubMed  Google Scholar 

  8. Benseler SM et al. (2005) Angiography-negative primary central nervous system vasculitis in children: a newly recognized inflammatory central nervous system disease. Arthritis Rheum 52: 2159–2167

    Article  Google Scholar 

  9. Aviv RI et al. (2007) Angiography of primary central nervous system angiitis of childhood: conventional angiography versus magnetic resonance angiography at presentation. AJNR Am J Neuroradiol 28: 9–15

    Article  CAS  Google Scholar 

  10. Lanthier S et al. (2005) Post-varicella arteriopathy of childhood: natural history of vascular stenosis. Neurology 64: 660–663

    Article  Google Scholar 

  11. Sébire G (2006) Transient cerebral arteriopathy in childhood. Lancet 368: 8–10

    Article  Google Scholar 

  12. Fullerton HJ et al. (2007) Risk of recurrent childhood arterial ischemic stroke in a population-based cohort: the importance of cerebrovascular imaging. Pediatrics 119: 495–501

    Article  Google Scholar 

  13. Wasserman BA et al. (2001) Reliability of normal findings on MR imaging for excluding the diagnosis of vasculitis of the central nervous system. AJR Am J Roentgenol 177: 455–459

    Article  CAS  Google Scholar 

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Correspondence to Susanne M Benseler.

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Cantez, S., Benseler, S. Childhood CNS vasculitis: a treatable cause of new neurological deficit in children. Nat Rev Rheumatol 4, 460–461 (2008).

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