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Focal and generalized bone loss in rheumatoid arthritis: separate or similar concepts?

Nature Clinical Practice Rheumatology volume 4, pages 402–403 (2008)Cite this article

In rheumatoid arthritis (RA), bone involvement presents as generalized osteoporosis, periarticular osteoporosis and erosions. Do these three bone-damage features in RA have a common cellular pathophysiological mechanism? If so, then therapeutic strategies that target this common cellular mechanism might benefit patients with active RA. Moreover, quantitative measurement of bone loss could be an alternative or additional outcome measure to radiographic joint damage for the assessment of bone involvement in RA.

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  1. Department of Rheumatology, Sørlandet Hospital, Service box 416, N-4604 Kristiansand S, Norway glenn.haugeberg@sshf.no

Authors and Affiliations

  1. G Haugeberg is a Professor in the Division of Rheumatology at the Norwegian University of Science and Technology, and a Consultant at the Department of Rheumatology, Sørlandet Hospital, Norway.,

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Haugeberg, G. Focal and generalized bone loss in rheumatoid arthritis: separate or similar concepts?. Nat Rev Rheumatol 4, 402–403 (2008). https://doi.org/10.1038/ncprheum0843

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