Does diuretic use increase the risk of recurrent gout flares?

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  1. 1

    Becker MA and Jolly M (2006) Hyperuricemia and associated diseases. Rheum Dis Clin N Am 32: 275–293

  2. 2

    Wallace KL et al. (2004) Increasing prevalence of gout and hyperuricemia over 10 years among older adults in a managed care population. J Rheum 31: 1582–1587

  3. 3

    Gurwitz JH et al. (1997) Thiazide diuretics and the initiation of anti-gout therapy. J Clin Epidemiol 50: 953–959

  4. 4

    Fang J and Alderman M (2000) Serum uric acid and cardiovascular mortality: the NHANES1 Epidemiologic Follow-Up Study, 1971–1992. National Health and Nutrition Examination Survey. JAMA 283: 2404–2410

  5. 5

    Janssens HJ et al. (2006) Gout, not induced by diuretics? A case–control study from primary care. Ann Rheum Dis 65: 1080–1083

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The synopsis was written by Rachel Murphy, Assistant Editor, Nature Clinical Practice.

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Correspondence to Michael A Becker.

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Competing interests

Professor MA Becker has declared that he is a consultant for TAP Pharmaceutical Products Inc, and on the Advisory Board for Savient Pharmaceuticals.

S Chohan declared she has no competing interests.

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