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How to judge a tumor marker

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References

  1. McShane LM et al. (2005) Reporting recommendations for tumor marker prognostic studies (REMARK). Nat Clin Pract Oncol 2: 416–422

    CAS  PubMed  Google Scholar 

  2. Bast RC et al. (2001) 2000 Update of recommendations for the use of tumor markers in breast and colorectal cancer: clinical practice guidelines of the American Society of Clinical Oncology. J Clin Oncol 19: 1865–1878

    Article  PubMed  Google Scholar 

  3. Chatfield C (1995) Model uncertainty, data mining and statistical inference. J R Stat Soc [Ser A] 158: 419–466

    Article  Google Scholar 

  4. Kattan MW (2003) Judging new markers by their ability to improve predictive accuracy. J Natl Cancer Inst 95: 634–635

    CAS  Article  PubMed  Google Scholar 

  5. Harrell FE et al. (1996) Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. Stat Med 15: 361–387

    Article  PubMed  Google Scholar 

  6. Kattan MW and Gonen M Prediction from multivariable regression models. Urol Oncol, in press

  7. Breiman L (2001) Statistical modeling: the two cultures. Stat Sci 16: 199–231

    Article  Google Scholar 

  8. Efron B and Tibshirani RJ (1998) An introduction to the bootstrap. NY: Chapman & Hall/CRC

    Google Scholar 

  9. Ehrenberg ASC and Bound JA (1993) Predictability and prediction. J R Stat Soc [Ser A] 156: 167–206

    Article  Google Scholar 

  10. Hayes DF et al. (1996) Tumor Marker Utility Grading System: a framework to evaluate clinical utility of tumor markers. J Natl Cancer Inst 88: 1456–1466

    CAS  Article  PubMed  Google Scholar 

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Correspondence to Ethan M Katz MS.

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Katz, E., Kattan, M. How to judge a tumor marker. Nat Rev Clin Oncol 2, 482–483 (2005). https://doi.org/10.1038/ncponc0318

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