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First-line treatment options for patients with metastatic colorectal cancer

Nature Clinical Practice Oncology volume 1, pages 70–71 (2004)Cite this article

boxed-textHurwitz H et al. (2004) Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 350: 2335–2342

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References

  1. Goldberg R et al. (2004) A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 22: 23–30

    Article  CAS  Google Scholar 

  2. Tournigand C et al. (2004) FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Oncol 22: 229–237

    Article  CAS  Google Scholar 

  3. Rothenberg M et al. (2001) Mortality associated with irinotecan plus bolus fluorouracil/leucovorin: summary findings of an independent panel. J Clin Oncol 19: 3801–3807

    Article  CAS  Google Scholar 

  4. Genentech letter to physicians dated 4 August 2004 http://www.gene.com/gene/products/information/oncology/avastin

  5. Schrag D (2004) The price tag on progress—chemotherapy for colorectal cancer. N Engl J Med 351: 317–319

    Article  CAS  Google Scholar 

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Acknowledgements

The synopsis was written by David Bruce, Nature Clinical Practice.

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  1. Professor of Medicine and Associate Dean for Clinical Research at the University of Chicago,

    Richard L Schilsky

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  1. Richard L Schilsky
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Correspondence to Richard L Schilsky.

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Schilsky, R. First-line treatment options for patients with metastatic colorectal cancer. Nat Rev Clin Oncol 1, 70–71 (2004). https://doi.org/10.1038/ncponc0035

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