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Lowering salt intake—an important strategy in the management of renal disease

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References

  1. He J et al. (1999) Dietary sodium intake and subsequent risk of cardiovascular disease in overweight adults. JAMA 282: 2027–2034

    Article  CAS  Google Scholar 

  2. Tuomilehto J et al. (2001) Urinary sodium excretion and cardiovascular mortality in Finland: a prospective study. Lancet 357: 848–851

    Article  CAS  Google Scholar 

  3. Verhave JC et al. (2004) Sodium intake affects urinary albumin excretion especially in overweight subjects. J Intern Med 256: 324–330

    Article  CAS  Google Scholar 

  4. Kitiyakara C et al. (2003) Salt intake, oxidative stress, and renal expression of NADPH oxidase and superoxide dismutase. J Am Soc Nephrol 14: 2775–2782

    Article  CAS  Google Scholar 

  5. Dworkin LD et al. (1996) Salt restriction inhibits renal growth and stabilizes injury in rats with established renal disease. J Am Soc Nephrol 7: 437–442

    CAS  PubMed  Google Scholar 

  6. Benstein JA et al. (1990) Superiority of salt restriction over diuretics in reducing renal hypertrophy and injury in uninephrectomized SHR. Am J Physiol 258: F1675–F1681

    CAS  PubMed  Google Scholar 

  7. Buter H et al. (1998) The blunting of the antiproteinuric efficacy of ACE inhibition by high sodium intake can be restored by hydrochlorothiazide. Nephrol Dial Transplant 13: 1682–1685

    Article  CAS  Google Scholar 

  8. Al-Awqati Q (2006) Evidence-based politics of salt and blood pressure. Kidney Int 69: 1707–1708

    Article  Google Scholar 

  9. Sacks FM et al. (2001) Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. DASH-Sodium Collaborative Research Group. N Engl J Med 344: 3–10

    Article  CAS  Google Scholar 

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Acknowledgements

The synopsis was written by Chloë Harman, Associate Editor, Nature Clinical Practice.

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Ritz, E. Lowering salt intake—an important strategy in the management of renal disease. Nat Rev Nephrol 3, 360–361 (2007). https://doi.org/10.1038/ncpneph0500

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