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Should triple therapy for Helicobacter pylori eradication be prescribed for 1 week or 2 weeks?

Nature Clinical Practice Gastroenterology & Hepatology volume 4, pages 596–597 (2007)Cite this article

boxed-textZagari RM et al. (2007) Comparison of 1 and 2 weeks of omeprazole, amoxicillin and clarithromycin treatment for Helicobacter pylori eradication: the HYPER study. Gut 56: 475–479

Increasing the duration of PPI triple therapy from 1 week to 2 weeks does not significantly improve eradication rates in patients infected with Helicobacter pylori

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References

  1. P Malfertheiner et al. (2007) The European Helicobacter Study Group (EHSG). Current concepts in the management of Helicobacter pylori infection: the Maastricht III Consensus Report. Gut 56: 772–781

    Article  CAS  Google Scholar 

  2. Ford A and Moayyedi P (2003) How can the current strategies for Helicobacter pylori eradication therapy be improved? Can J Gastroenterol 17 (Suppl B): 36B–40B

    Article  Google Scholar 

  3. Kim BG et al. (2007) Comparison of 7-day and 14-day proton pump inhibitor-containing triple therapy for Helicobacter pylori eradication: neither treatment duration provides acceptable eradication rate in Korea. Helicobacter 12: 31–35

    Article  CAS  Google Scholar 

  4. Paoluzi P et al. (2006) 2-week triple therapy for Helicobacter pylori infection is better than 1-week in clinical practice: a large prospective single-center randomized study. Helicobacter 11: 562–528

    Article  Google Scholar 

  5. Vaira D et al. (2007) Sequential therapy versus standard triple-drug therapy for Helicobacter pylori eradication: a randomized trial. Ann Intern Med 146: 556–563

    Article  Google Scholar 

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Acknowledgements

The synopsis was written by Rachel Jones, Associate Editor, Nature Clinical Practice.

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  1. MUMC, 1200 Main Street West, West Hamilton, ON L8N 3Z5, Canada moayyep@mcmaster.ca

Authors and Affiliations

  1. P Moayyedi is a Professor and Director of the Division of Gastroenterology at the McMaster University Medical Center, Hamilton, ON, Canada.,

    Paul Moayyedi

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Competing interests

The author has acted as a Consultant for AstraZeneca, Nycomed and Janssen-Ortho, and is on the Speaker's Bureau for AstraZeneca, Axcan, and Nycomed. His position is also partially funded by AstraZeneca.

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Moayyedi, P. Should triple therapy for Helicobacter pylori eradication be prescribed for 1 week or 2 weeks?. Nat Rev Gastroenterol Hepatol 4, 596–597 (2007). https://doi.org/10.1038/ncpgasthep0956

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